Repurposing a microfluidic formulation device for automated DNA construction
نویسندگان
چکیده
منابع مشابه
Developing a Device for Automated Peritoneal Dialysis
Background: Peritoneal dialysis (PD) is an efficient alternative for hemodialysis. Removal of waste metabolites and excess water from the blood circulation are the two main tasks done during dialysis. These are done by using a filter; in PD, the naturally semi-permeable peritoneal membrane acts as the filter. Automated PD machines control intelligently the operations to enhance the efficiency a...
متن کاملMagnetophoretic-based microfluidic device for DNA Concentration.
Nucleic acids serve as biomarkers of disease and it is highly desirable to develop approaches to extract small number of such genomic extracts from human bodily fluids. Magnetic particles-based nucleic acid extraction is widely used for concentration of small amount of samples and is followed by DNA amplification in specific assays. However, approaches to integrate such magnetic particles based...
متن کاملA Microfluidic Device for DNA Tile Self-assembly
In order to self-assemble desired DNA nanostructure, it is necessary to suppress assembly errors caused by fluctuations of temperature and concentration. We propose a microfluidic device to directly control such environmental parameters of DNA self-assembly. In this paper, some experimental results concerned with key processes of self-assembly in the device, such as immobilizing DNA strands in ...
متن کاملMicrofluidic device for rapid (<15 min) automated microarray hybridization.
BACKGROUND Current hybridization protocols on microarrays are slow and need skilled personnel. Microfluidics is an emerging science that enables the processing of minute volumes of liquids to perform chemical, biochemical, or enzymatic analyzes. The merging of microfluidics and microarray technologies constitutes an elegant solution that will automate and speed up microarray hybridization. ME...
متن کاملAutomated formation of lipid-bilayer membranes in a microfluidic device.
Although membrane channel proteins are important to drug discovery and hold great promise as engineered nanopore sensing elements, their widespread application to these areas has been limited by difficulties in fabricating planar lipid-bilayer membranes. We present a method for forming these sub-5-nm-thick free-standing structures based on a self-assembly process driven by solvent extraction in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2020
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0242157