Resectability of colorectal liver metastases: an evolving definition
نویسندگان
چکیده
منابع مشابه
Expanding criteria for resectability of colorectal liver metastases.
Surgical resection is the treatment of choice in patients with colorectal liver metastases, with 5-year survival rates reported in the range of 40%-58%. Over the past 10 years, there has been an impetus to expand the criteria for defining resectability for patients with colorectal metastases. In the past, such features as the number of metastases (three to four), the size of the tumor lesion, a...
متن کاملEvaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study.
BACKGROUND/AIM The Kyushu Study Group of Clinical Cancer (KSCC) previously reported the safety and efficacy of neoadjuvant chemotherapy with mFOLFOX6 + bevacizumab for H2/H3 liver metastases of colorectal cancer. The aim of the current study was to evaluate the resectability of these metastases before and after chemotherapy as determined by independent liver surgeons. METHODS Between May 2008...
متن کاملStrategies to increase the resectability of liver metastases from colorectal cancer.
Liver resection can provide long-term survival and cure for patients with colorectal liver metastases but is feasible in only 15-25% of patients. In the last few years several major developments have contributed to increase this resectability rate. Neo-adjuvant chemotherapy can provide response rates as high as 50%, allowing surgery in about 10-15% of patients initially deemed unresectable. Pat...
متن کاملColorectal liver metastases.
BACKGROUND Despite major advances in therapies for liver metastases, colorectal cancer remains one of the commonest causes of cancer-related deaths in the UK. SOURCES OF DATA The international literature on the management of colorectal liver metastases (CLM) was reviewed. AREAS OF AGREEMENT Due to a combination of highly active systemic agents and low perioperative mortality achieved by hig...
متن کاملColorectal liver metastases
Each year in the UK, between 1214 000 people develop liver metastases from colorectal cancer. These metastases will contribute to the death ofthe patient in about 80% ofcases. Treatments aimed at these tumours are best administered when the tumour is small. Current investigative methods allow tumours as small as 0.5 mm to be detected, and should be offered to all colorectal cancer patients at r...
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ژورنال
عنوان ژورنال: HPB
سال: 2012
ISSN: 1365-182X
DOI: 10.1111/j.1477-2574.2012.00451.x