Residence Time Section Evaluation and Feasibility Studies for One-Column Simulated Moving Bed Processes (1-SMB)
نویسندگان
چکیده
The simulated moving bed (SMB) is a well-established, fully continuous process for chromatographic separation of difficult tasks with overlapping peaks, but it relatively complex. 1-SMB, which uses only one column includes residence time zones to preserve concentration profiles, simpler semi-continuous alternative. This work examines the possible design these zones. Simulation studies were conducted investigate dependence metrics, such as purity, yield, productivity, and eluent consumption, on fluid dynamics. No deterioration in purity was observed, other variables remained constant over wide range axial dispersion before decreasing sharply. Pilot-scale experiments various devices, including coiled flow inverters, eluate recycling packed columns, tank arrangements, validate apparatus implementations dynamic measurements. It demonstrated that 1-SMB offers similar performance 4-SMB, albeit reduced yield lower complexity.
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ژورنال
عنوان ژورنال: Processes
سال: 2023
ISSN: ['2227-9717']
DOI: https://doi.org/10.3390/pr11061634