Response rate and subjective memory after electroconvulsive therapy in depressive disorders with psychiatric comorbidity

• Psychiatric comorbidity is associated with lower odds of response to ECT for depression. This primarily among younger and less depressed patients. The rates were still higher than reported pharmacotherapies. should not exclude patients from treatment ECT. Response after tolerability electroconvulsive therapy (ECT) in depressive disorders psychiatric are uncertain. Data on a episode first course collected the Swedish National Quality Register Logistic regression analyses, adjusted gender, age, severity, used compare without comorbidity. clinical assessment Clinical Global Impression - Improvement Scale was 4413 memory item Comprehensive Rating subjective impairment rating 3497 In disorder comorbid personality or anxiety disorder, 62.7% 73.5%, respectively, responded compared 84.9% [adjusted ratio (aOR) 0.43, 95% confidence interval (CI) 0.34–0.55, aOR 0.61, CI 0.51–0.73, respectively]. proportion responding alcohol use 77.1%, which significantly different that (aOR 0.75, 0.57–1.01). impact decreased age severity. Subjective ratings did differ between Observational non-validated data. rate depression may be concurrent disorder; however, majority respond implies