Restricted Diffusion MRI Lesions in HIV-Associated CMV Encephalitis

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Cytomegalovirus (CMV) Encephalitis in HIV Patients

It is hypothesized that impaired CD4 cell functioning is attributable to viral replication. Most cases of CMV encephalitis occur when CD4 counts fall below 50, however patients may be predisposed to CMV infection prior to depletion of CD4 [1]. Previous opportunistic infections (OIs), a high level of CMV viremia, and high plasma HIV RNA levels (>100,000 copies/mL) are other reported risk factors...

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Combined HIV-CMV encephalitis presenting with brainstem signs.

Two cases of combined HIV-CMV encephalitis are described. One presented with a sixth nerve palsy and a tetraparesis, the other with an internuclear ophthalmoplegia. Pathologically brain stem involvement was predominantly due to CMV.

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Comparison of magnetic resonance imaging with neuropathological findings in the diagnosis of HIV and CMV associated CNS disease in AIDS.

OBJECTIVES To compare the results of clinical assessment and MRI with neuropathological findings in the diagnosis of HIV and cytomegalovirus (CMV) associated CNS disease. METHODS A retrospective study of 35 patients infected with HIV who were examined at necropsy between four and 70 (median 20) days after neurological assessment and MRI. RESULTS Of the 35 patients, 19 had diffuse white matt...

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CMV-associated encephalitis and antineuronal autoantibodies - a case report

BACKGROUND Human cytomegalovirus (CMV) is an ubiquitous pathogen capable of modulating the host immune system. Immune dysfunction is common during CMV infection and includes autoimmune phenomena. Here we focus on a case of primary CMV infection associated with encephalopathy in a patient with a rudimentary spleen. We discuss diagnostic challenges and immunological aspects as well as the hypothe...

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ژورنال

عنوان ژورنال: The Neurohospitalist

سال: 2017

ISSN: 1941-8744,1941-8752

DOI: 10.1177/1941874417698325