Resveratrol: Evidence for Its Nephroprotective Effect in Diabetic Nephropathy
نویسندگان
چکیده
منابع مشابه
Resveratrol Attenuates Diabetic Nephropathy via Modulating Angiogenesis
Angiogenesis plays an important role in the pathogenesis of diabetic nephropathy (DN). In the present study, we investigated the therapeutic potential of resveratrol, a polyphenol with antiangiogenic activity in DN. In a type 1 diabetic rat model, resveratrol treatment blunted the increases of urine albumin excretion, kidney weight and creatinine clearance rate. The increases of glomerular diam...
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Aims: Diabetic nephropathy is one of the consequences of type 1 and type 2 diabetes and one of the main causes of End-Stage Renal Disease (ESRD) as well as an important risk factor for cardiovascular morbidity and death. The aim of this study was to identify the risk factors for diabetic nephropathy in diabetic patients. Instruments & Methods: In this cross-sectional descriptive study, 121 pat...
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Diacylglycerol (DAG) has been reported to reduce the serum lipid and glucose levels more effectively compared with triacylglycerol (TAG). The present study examined the long-term effects of dietary DAG on rats with type 2 diabetic nephropathy (DN). The type 2 DN model was established by administering a high-fat and high-calorie diet along with an intraperitoneal injection of 35 mg/kg body weigh...
متن کاملResveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats.
Diabetic nephropathy is a serious microvascular complication and one of the main causes of end-stage renal disease. Various studies have revealed that increased oxidative stress is a major pathophysiological mechanism which is involved in the etiology of diabetic nephropathy. Resveratrol, a polyphenolic phytoalexin present in red wine, is known to possess potent antioxidant properties and thus ...
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Protection against diabetic nephropathy (DN) is one of the main targets in diabetes treatment and present study evaluates the nephroprotective effect of Carica papaya L. in streptozotocin (STZ) induced diabetic rats. DN rats were treated with 1.5 and 2.5 gm/dl C. papaya leaf extract for 6 weeks to determine its nephroprotective effect with different parameters. Pimagedine (1 ml/mg) served as a ...
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ژورنال
عنوان ژورنال: Advances in Nutrition
سال: 2020
ISSN: 2161-8313,2156-5376
DOI: 10.1093/advances/nmaa075