Reverse engineering systems models of regulation: discovery, prediction and mechanisms
نویسندگان
چکیده
منابع مشابه
Reverse engineering models of cell cycle regulation.
From general considerations of the basic physiological properties of the cell division cycle, we deduce what the dynamical properties of the underlying molecular control system must be. Then, taking a few hints from the biochemistry of cyclin-dependent kinases (the master regulators of the eukaryotic cell cycle), we guess what molecular mechanisms must be operating to produce the desired dynami...
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ژورنال
عنوان ژورنال: Current Opinion in Biotechnology
سال: 2012
ISSN: 0958-1669
DOI: 10.1016/j.copbio.2011.12.005