Reversibility of alcohol-related brain atrophy
نویسندگان
چکیده
منابع مشابه
Progressive Brain Atrophy due to Chronic Alcohol Abuse.
The most commonly reported findings in the brains of alcoholics are sulcal widening and ventricular enlargement as well as cortical white matter shrinkage. The frontal lobes appear to be more vulnerable to alcoholrelated brain damage than other cerebral regions. The cerebellum, cortical-limbic circuits, skeletal muscle, and peripheral nerves are also important targets of chronic alcohol-related...
متن کاملMolecular genetics of alcohol-related brain damage.
AIMS In the scientific literature it has been repeatedly hypothesized that there is a heritable susceptibility to thiamine deficiency comparable to other hereditary metabolic disorders. The aim of this paper is to review the most recent knowledge on the genetic susceptibility to the development of alcohol-related Wernicke-Korsakoff syndrome (WKS). METHODS A literature review was carried out l...
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Excessive alcohol use can cause structural and functional abnormalities of the brain and this has significant health, social and economic implications for most countries in the world. Even heavy social drinkers who have no specific neurological or hepatic problems show signs of regional brain damage and cognitive dysfunction. Changes are more severe and other brain regions are damaged in patien...
متن کاملCortical complexity as a measure of age-related brain atrophy
The structure of the human brain changes in a variety of ways as we age. While a sizeable literature has examined age-related differences in cortical thickness, and to a lesser degree, gyrification, here we examined differences in cortical complexity, as indexed by fractal dimensionality in a sample of over 400 individuals across the adult lifespan. While prior studies have shown differences in...
متن کاملAlcohol-Related Brain Damage in Humans
Chronic excessive alcohol intoxications evoke cumulative damage to tissues and organs. We examined prefrontal cortex (Brodmann's area (BA) 9) from 20 human alcoholics and 20 age, gender, and postmortem delay matched control subjects. H & E staining and light microscopy of prefrontal cortex tissue revealed a reduction in the levels of cytoskeleton surrounding the nuclei of cortical and subcortic...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2000
ISSN: 1527-6465,1527-6473
DOI: 10.1053/lv.2000.7579