Reversible inactivation of AT2angiotensin II receptor from cysteine-disulfide bond exchange
نویسندگان
چکیده
منابع مشابه
Reversible Inactivation of Cytochrome Oxidase by Disulfide Bond Reagents.
Recent studies on the chemical nature of cytochrome oxidase (cytochrome c :02 oxidoreductase, EC 1.9.3.1) have been concerned largely with the structure of its iron-porphyrin prosthetic group (cj. (l)), the importance of copper as an integral component of the enzyme (e.g. (2-5)), and the possible role of a lipid factor (e.g. (6-8)). By contrast, little work has been done on the nature of the fu...
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Disulfide bonds tie different peptide chains together and lock folded dipeptide chains into particular configurations. It is of interest to learn whether there is a differential susceptibility of viruses to inactivation by disulfide bond reduction. This may lead to information concerning differences in virion structures and may help in grouping them in different morphological categories. Dithio...
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The zinc(II) complex [Zn2(dmdtc)2(μ-dmdtc)2] has been synthesized directly from thiram ligand, containing a disulfide bond {dmdtc = N,N-dimethyldithiocarbamate; thiram = N,N-tetramethylthiuram disulfide}, and characterized by elemental analysis and spectroscopic methods. Surprisingly thiram, undergoes a reductive disulfide bond scission upon reaction with Zn2+ in methanolic media to give the [Z...
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Raman spectra of several compounds containing the CS-SC moiety were obtained (in the solid phase) from 450-800 cm(-1) to investigate the S-S and C-S stretching behavior. The S-S stretching frequency varied linearly with the CS-SC dihedral angle (obtained from either x-ray or neutron diffraction or ultraviolet absorption) for compounds whose CC-SS dihedral angles were not very different. The rat...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2000
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(00)02141-4