Right atrial function in HFpEF in sinus rhythm vs. atrial fibrillation

Abstract Aims We sought to study the prognostic impact of right atrial (RA) size and function in patients with heart failure preserved ejection fraction (HFpEF) sinus rhythm (SR) vs. fibrillation (AF). Methods results Consecutive HFpEF were enrolled indexed RA volumes emptying fractions (RA-EF) assessed by cardiac magnetic resonance imaging (CMR). For SR during CMR feature tracking wall was performed (Figure 1). In addition, all underwent left catheterization, 6 min walk test, N-terminal prohormone brain natriuretic peptide (NT-proBNP) evaluation. prospectively followed used Cox regression models determine association a composite endpoint hospitalization cardiovascular death. A total 188 (71% female patients, 70±8 years old) included whom 96 (51%) SR. Eighty-five reached combined follow-up 72 (33–101) months. After multivariate cox analysis adjusted for age, NT-proBNP level, ventricular HF functional class, impaired strain 1A) (HR 0.959; 95% CI [0.924–0.996], P=0.024), conduit 0.944; [0.898–0.993], P=0.027) rate 1B) 0.990; [0.883–0.998], P=0.013) significantly associated adverse outcome (Table persistent AF, no parameter related after analysis. Conclusions SR, parameters show best outcome. lose their ability. Funding Acknowledgement Type funding sources: None.