Risk Factors for Adverse Neurodevelopment in Transient or Persistent Congenital Hyperinsulinism
نویسندگان
چکیده
منابع مشابه
Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism
BACKGROUND Congenital hyperinsulinism (CHI) is a rare but severe disorder of hypoglycemia in children, often complicated by brain injury. In CHI, the long-term prevention of hypoglycemia is dependent on reliable enteral intake of glucose. However, feeding problems (FPs) often impede oral glucose delivery, thereby complicating the management of hypoglycemia. FPs have not been systematically char...
متن کامل[Congenital hyperinsulinism].
In the last five years, our knowledge about the heterogenous syndrome of congenital hyperinsulinism (HI) has expanded explosively. HI may be familiar or sporadic, mild or severe, transitory or persistent, and histologically focal or diffuse. At least 63 disease-causing mutations have been found in the genes for the beta cell's ATP-dependent potassium channel, whose elements are the sulphonylure...
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With a systematically sampled population of children aged under 5 attending this centre for diarrhoeal disease research during 1983-5 a retrospective analysis of persistent diarrhoea (defined as greater than 14 days' duration) was performed to identify the possible risk factors for this syndrome. Of the 4155 children included in the analysis, 410 (10%) gave a history of persistent diarrhoea. A ...
متن کامل[Risk factors for persistent diarrhea].
The current concepts in persistent diarrhoea (PD) are reviewed. 102 patients with acute diarrhoea and 85 with PD are studied. All were less than one year old. Information about age, nutritional status, time of breast feeding, previous episodes of acute and persistent diarrhoea and the previous use of drugs is registered. Microbiological and parasitologics studies were done to identify enteric p...
متن کاملtransient hyperinsulinism in an asphyxiated small for gestation infant
transient hyperinsutinism has been implicated in the prolonged hypoglycemia observed in small for gestational age or asphyxiated newborns. tiiesc infants are at high risk for severe and permanent brain damage, thus necessitating appropriate diagnosis and correct treatment. a term male asphyxiated small for gestation 30 day infant with long-standing hypoglycemia and intractable seizures was mana...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2020
ISSN: 1664-2392
DOI: 10.3389/fendo.2020.580642