Risk Maps of Lassa Fever in West Africa

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Risk Maps of Lassa Fever in West Africa

BACKGROUND Lassa fever is caused by a viral haemorrhagic arenavirus that affects two to three million people in West Africa, causing a mortality of between 5,000 and 10,000 each year. The natural reservoir of Lassa virus is the multi-mammate rat Mastomys natalensis, which lives in houses and surrounding fields. With the aim of gaining more information to control this disease, we here carry out ...

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Mastomys natalensis and Lassa Fever, West Africa

PCR screening of 1,482 murid rodents from 13 genera caught in 18 different localities of Guinea, West Africa, showed Lassa virus infection only in molecularly typed Mastomys natalensis. Distribution of this rodent and relative abundance compared with M. erythroleucus correlates geographically with Lassa virus seroprevalence in humans.

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Lassa fever: another threat from West Africa

Lassa fever, a zoonotic viral infection, is endemic in West Africa. The disease causes annual wide spread morbidity and mortality in Africa, and can be imported by travelers. Possible importation of Lassa fever and the potential for the use of Lassa virus as an agent of bioterrorism mandate clinicians in Israel and other countries to be vigilant and familiar with the basic characteristics of th...

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Awareness of Lassa Fever in a Rural Community in South West Nigeria

Background: Lassa fever is an acute, virulent viral haemorrhagic illness with high morbidity and mortality rates. Its awareness remain low in sub urban or rural community. This study was carried out to assess the awareness of Lassa fever of a rural community in the south western part of Nigeria. Methodology: A descriptive cross sectional study of 122 respondents prior to a sensitization semina...

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Mapping Transmission Risk of Lassa Fever in West Africa: The Importance of Quality Control, Sampling Bias, and Error Weighting

Lassa fever is a disease that has been reported from sites across West Africa; it is caused by an arenavirus that is hosted by the rodent M. natalensis. Although it is confined to West Africa, and has been documented in detail in some well-studied areas, the details of the distribution of risk of Lassa virus infection remain poorly known at the level of the broader region. In this paper, we exp...

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ژورنال

عنوان ژورنال: PLoS Neglected Tropical Diseases

سال: 2009

ISSN: 1935-2735

DOI: 10.1371/journal.pntd.0000388