Risk of Late Postoperative Recurrence of Crohn’s Disease in Patients in Endoscopic Remission After Ileocecal Resection, Over 10 Years at Multiple Centers

Background & AimsThe risk of recurrence Crohn’s disease (CD) from 1 to 10 years after surgery despite initial endoscopic remission (late post-operative recurrence) is not clear.MethodsWe performed a retrospective study, at 3 inflammatory bowel (IBD) centers in France and Belgium, all patients with CD (n = 86) undergoing an ileocecal resection curative intent 2006 through 2016 who did have evidence for (Rutgeerts score less than i2) their baseline assessment. Postoperative endoscopy was defined as composite endpoint least the following: clinical recurrence, IBD-related hospitalization, occurrence damage, need balloon dilatation anastomosis, repeat surgery. Risk mucosal progression studied secondary outcome.ResultsThe median time between 7 months (IQR, 5.7–9.5 months); 40 (46.5%) received medical prophylaxis this period. The follow-up 3.5 1.6–5.3 years). Thirty-five (40.7%) had late CD, 14.2 6.3–26.1 months). Recurrence status differ significantly Rutgeerts scores i0 (20/55) or i1 (15/31) (P .28) independent (16/40 prophylactic therapy vs 19/46 without therapy; P .90). Mucosal progressed 29 71 (40.8%) available data. We identify factors progression.ConclusionsAmong treated by resection, 40% remission, years. Tight monitoring these recommended beyond 18 months. clear. outcome. progression. Among