Rivastigmine Loaded L-Lactide-Depsipeptide Polymeric Nanoparticles: Decisive Formulation Variables Optimization

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Rivastigmine-Loaded L-Lactide-Depsipeptide Polymeric Nanoparticles: Decisive Formulation Variable Optimization

The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer for the development of rivastigmine-loaded polymeric nanoparticles. L-lactide-depsipeptide synthesis was based on the ring opening polymerization reaction of L-lactide with the cyclodepsipeptide, cyclo(Glc-Leu), using tin 2-ethyl hexanoate as an initiator. Rivastigmine-loaded nanoparticles were prepared by...

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ژورنال

عنوان ژورنال: Scientia Pharmaceutica

سال: 2013

ISSN: 0036-8709,2218-0532

DOI: 10.3797/scipharm.1211-20