Robustness and Corrections for Sample Size Adaptation Strategies Based on Effect Size Estimation
نویسندگان
چکیده
منابع مشابه
Robustness and Corrections for Sample Size Adaptation Strategies Based on Effect Size Estimation
The robustness of the adaptation of the sample size for a phase III trial based on phase II data is studied -when phase III is lower than phase II effect size. Conservative sample size estimation strategies are compared. When the rate between phase III and phase II effect size is greater than 0.8, Calibrated Optimal Strategy provides acceptable results. A correction for balancing the structural...
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ژورنال
عنوان ژورنال: Communications in Statistics - Simulation and Computation
سال: 2011
ISSN: 0361-0918,1532-4141
DOI: 10.1080/03610918.2011.568152