Routine Diagnosis of Tuberculous Meningitis with MODS Assay
نویسندگان
چکیده
منابع مشابه
Rapid diagnosis of tuberculous meningitis by a dot-immunobinding assay.
In this study, a dot-immunobinding assay (Dot-Iba) was standardized to measure circulating antimycobacterial antibodies in the cerebrospinal fluid (CSF) specimens for the rapid laboratory diagnosis of tuberculous meningitis (TBM). Specific CSF-IgG antibody to Mycobacterium tuberculosis from a culture proven patient with TBM was isolated and coupled with activated Cynogen bromide-Sepharose 4B. U...
متن کاملEvaluation of the MODS Culture Technique for the Diagnosis of Tuberculous Meningitis
BACKGROUND Tuberculous meningitis (TBM) is a devastating condition. The rapid instigation of appropraite chemotherapy is vital to reduce morbidity and mortality. However rapid diagnosis remains elusive; smear microscopy has extremely low sensitivity on cerebrospinal fluid (CSF) in most laboratories and PCR requires expertise with advanced infrastructure and has sensitivity of only around 60% un...
متن کاملMODS assay for the diagnosis of TB.
To the Editor: In their article on the use of microscopic-observation drug-susceptibility (MODS) culture for the diagnosis and direct detection of multidrug-resistant tuberculosis, Moore et al. (Oct. 12 issue)1 state that MODS culture offers faster and more sensitive results than existing goldstandard methods. This study is one of the few performed in a target population with a rather simple an...
متن کاملEvaluating Auto-mods Assay for Tuberculosis Diagnosis
Address for Correspondence: 17 Boonchai Chaiyasirinroje, B.Sc. 18 1050/1 Satarnpayabarn Rd., Muang District 19 Chiang Rai 57000, Thailand 20 Tel: +66-53-713135 21 Fax: +66-53-752448 22 Email: [email protected] 23 24 Address for other authors: 25 Linwei Wang, M.Sc. Candidate 26 Edmonton Clinic Health Academy 4-051 27 11405 87 Avenue, Edmonton, Alberta, Canada, T6G 1C9 28 Email: linwei1@ualberta...
متن کاملImproving the bacteriological diagnosis of tuberculous meningitis.
We made a bacteriological diagnosis of tuberculous meningitis in 107 of 132 (81%) adults with clinical tuberculous meningitis: acid-fast bacilli were seen in 77 of 132 (58%) and cultured from 94 of 132 (71%). Volume of cerebrospinal fluid, duration of symptoms, cerebrospinal fluid neutrophils, lactate, and glucose were all independently associated with bacteriological confirmation.
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2008
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2008.05.856