Sarcosine Biosensor Based on Pt/g-C₃N₄ Nanocomposites with High Electrocatalytic Activity

Sarcosine has been shown to be a new biomarker for prostate cancer that is superior prostate-specific antigen (PSA). By detecting the concentration of sarcosine in human body, accurate screening and diagnosis can achieved clinical practice. However, level extremely low serum or urine, detection difficult. More work needed prepare biosensors with good anti-interference performance. In this work, we prepared biosensor using highly electrocatalytically active nanocomposite comprising platinum/carbon nitride (Pt/g-C 3 N 4 ) as electrode modification material. The porous lamellar graphite phase carbon (g-C prevents agglomeration Pt nanoparticles keeps dispersed state. constructed achieves high sensitivity selectively detect concentrations sarcosine. Its linear range 2–70 ? M, limit (LOD) 0.8 M (S/N = 3). shows relatively performance terms resistance interference caused by electroactive substances provides potential applied