Scabraside D Extracted from Holothuria scabra Induces Apoptosis and Inhibits Growth of Human Cholangiocarcinoma Xenografts in Mice
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Scabraside D from Holothuria scabra Induces Apoptosis and Inhibits Growth of Human Cholangiocarcinomas in Mice
Cholangiocarcinoma (CCA), is an incurable cancer of the biliary epithelium, and is an important public health problem in many Asian countries (Sripa and Pairojkul, 2008; Shin et al., 2010; Sripa et al., 2011). High prevalence is found in northeast Thailand, where people eat raw freshwater fish infested with Opisthorchis viverrini, the parasitic platyhelminth associated with CCA (Haswell-Elkins ...
متن کاملScabraside D Effects on Apoptosis and Metastasis via iNOS and STAT-3 Expression in Human Cholangiocarcinoma Xenografts
Cholangiocarcinoma (CCA) is a cancer that originates from the bile duct epithelial cells. It is an increasing health problem worldwide (Gores, 2003). The highest incident rate is found in northeast Thailand, where people eat raw freshwater fish infested with liver fluke (Opisthorchis viverrini), the parasitic platyhelminth concerned with CCA (Haswell-Elkins et al., 1994). This cancer is one of ...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2016
ISSN: 1513-7368
DOI: 10.7314/apjcp.2016.17.2.511