SCALE-PWI: A Pulse Sequence for Absolute Quantitative Cerebral Perfusion Imaging
نویسندگان
چکیده
منابع مشابه
SCALE PWI: A Pulse Sequence for Quantitative Cerebral Perfusion Imaging
INTRODUCTION Quantitative cerebral perfusion is a fundamental physiologic parameter that reflects the severity and progression of a broad range of pathologies including: cancer, stroke, Alzheimer’s Disease, and cerebrovascular occlusive disease. The “Bookend” technique [1,2] allows quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) with dynamic susceptibility contrast (...
متن کاملSCALE-PWI: A pulse sequence for absolute quantitative cerebral perfusion imaging.
The Bookend technique is a magnetic resonance imaging (MRI) dynamic susceptibility contrast method that provides reliable quantitative measurement of cerebral blood flow (CBF) and cerebral blood volume (CBV). The quantification is patient specific, is derived from a steady-state measurement of CBV, and is obtained from T(1) changes in the white matter and the blood pool after contrast agent inj...
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INTRODUCTION Quantitative cerebral perfusion has been achieved via the Bookend technique [1,2] using dynamic susceptibility contrast (DSC) MRI and T1 changes in normal white matter (WM) in relation to the changes in the blood pool in a calibration slice, after contrast injection. Quantitative cerebral blood flow (qCBF), quantitative cerebral blood volume (qCBV) and mean transit time (MTT) measu...
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INTRODUCTION Quantitative cerebral perfusion is a fundamental physiologic parameter that reflects the severity and progression of a broad range of pathologies, such as stroke, cancer, Alzheimer’s Disease, cerebrovascular occlusive disease, and multiple sclerosis. An accelerated and simplified implementation of the multi-scan Bookend technique [1,2], which has been shown to provide reproducible,...
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BACKGROUND Arterial stiffness is a well-established indicator of cardiovascular disease outcome. Pulse Wave Velocity (PWV) is a surrogate for arterial stiffness that is measured either globally using carotid to femoral applanation tonometry or locally using biomedical imaging methods. Pulse Wave Imaging (PWI) is an ultrasound-based method for both qualitative visualisation of pulse wave propaga...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2010
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2010.215