Scaling law and universal drop size distribution of coarsening in conversion-limited phase separation

نویسندگان

چکیده

Phase separation is not only ubiquitous in diverse physical systems, but also plays an important organizational role inside biological cells. However, experimental studies of intracellular condensates (drops with condensed concentrations specific collections proteins and nucleic acids) have challenged the standard coarsening theories phase separation. Specifically, rates observed are unexpectedly slow for many condensates. Recently, Folkmann, et al. [Science {\bf 373}, 1218 (2021)] argued that rate can be caused by conversion a condensate constituent between state dilute state. A consequence this conversion-limited picture (Lifshitz-Slyozov--Wagner Ostwald ripening drop coalescence schemes) no longer apply. Surprisingly, I show here model equations instead mapped onto grain growth single-phase material three dimensions. further elucidate universal behavior late stage using analytical numerical methods.

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ژورنال

عنوان ژورنال: Physical review research

سال: 2021

ISSN: ['2643-1564']

DOI: https://doi.org/10.1103/physrevresearch.3.043081