Scoring function for automated assessment of protein structure template quality

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Scoring function for automated assessment of protein structure template quality.

We have developed a new scoring function, the template modeling score (TM-score), to assess the quality of protein structure templates and predicted full-length models by extending the approaches used in Global Distance Test (GDT)1 and MaxSub.2 First, a protein size-dependent scale is exploited to eliminate the inherent protein size dependence of the previous scores and appropriately account fo...

متن کامل

Gaia: automated quality assessment of protein structure models

MOTIVATION Increasing use of structural modeling for understanding structure-function relationships in proteins has led to the need to ensure that the protein models being used are of acceptable quality. Quality of a given protein structure can be assessed by comparing various intrinsic structural properties of the protein to those observed in high-resolution protein structures. RESULTS In th...

متن کامل

Structural bioinformatics Gaia: Automated Quality Assessment of Protein Structure Models

Supplementary Figure S1. Parameters used for surface area and void calculations. For any two overlapping atoms i and j, various distances and angles are represented in the figure. These parameters are used in different equations shown in the main text for computation of MSA/SASA and void volume.

متن کامل

QMEAN: A comprehensive scoring function for model quality assessment.

In protein structure prediction, a considerable number of alternative models are usually produced from which subsequently the final model has to be selected. Thus, a scoring function for the identification of the best model within an ensemble of alternative models is a key component of most protein structure prediction pipelines. QMEAN, which stands for Qualitative Model Energy ANalysis, is a c...

متن کامل

Amino acid scoring patterns for protein quality assessment.

The 1985 FAO/WHO/UNU protein report defined reference amino acid patterns for infants based on breast milk and for preschool children, schoolchildren and adults from age specific estimates of dietary indispensible amino acid requirements divided by the safe protein requirement for each age group. This report argued that the protein quality of a diet should be estimated from its digestibility ad...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics

سال: 2007

ISSN: 0887-3585

DOI: 10.1002/prot.21643