Secretion of latent type IV procollagenase and active type IV collagenase by testicular cells in culture

Activin A Stimulates Type IV Collagenase

the investigation of the relationship between type a and type b personalities and quality of translation

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Type IV secretion and H.pylori transformation

Helicobacter pylori colonizes the gastric mucosa of humans and, if left untreated, this will result in a lifelong gastritis. Although infection is usually asymptomatic, it can manifest clinically as peptic or duodenal ulcers. Additionally, colonization with H.pylori is believed to induce gastric atrophy and increase the risk of gastric cancer. New genotypes of H. pylori are generated by recombi...

92-kD type IV collagenase mediates invasion of human cytotrophoblasts

The specialized interaction between embryonic and maternal tissues is unique to mammalian development. This interaction begins with invasion of the uterus by the first differentiated embryonic cells, the trophoblasts, and culminates in formation of the placenta. The transient tumor-like behavior of cytotrophoblasts, which peaks early in pregnancy, is developmentally regulated. Likewise, in cult...

Structure of the human type IV collagenase gene.

The structure of the gene for human 70-kDa type IV collagenase (gelatinase) was determined. Three overlapping genomic clones were isolated and shown to contain 0.4 kilobase (kb) of the 5'-flanking region, the 27-kb structural gene, and 4.5 kb of the 3'-flanking region. The gene has 13 exons that vary in length from 110 to 901 base pairs (bp) and 12 introns that range from 175 to 4350 bp. Alignm...