Selective vulnerability in neurodegenerative diseases
نویسندگان
چکیده
منابع مشابه
From Intrinsic Firing Properties to Selective Neuronal Vulnerability in Neurodegenerative Diseases
Neurodegenerative diseases (NDDs) involve years of gradual preclinical progression. It is widely anticipated that in order to be effective, treatments should target early stages of disease, but we lack conceptual frameworks to identify and treat early manifestations relevant to disease progression. Here we discuss evidence that a focus on physiological features of neuronal subpopulations most v...
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ژورنال
عنوان ژورنال: Nature Neuroscience
سال: 2018
ISSN: 1097-6256,1546-1726
DOI: 10.1038/s41593-018-0221-2