Sensor platforms of Alpha-fetoprotein screening test for hepatocellular carcinoma detection by Surface Plasmon Resonance technique
نویسندگان
چکیده
Abstract The objective of this paper is to present the sensor platforms for alpha-fetoprotein (AFP), detection which a biomarker Hepatocellular carcinoma. experiments were designed investigate various AFP via surface Plasmon resonance (SPR) technique. In each step immobilization, antiAFP-AFP interaction and enhancing signal platform was used without fluorescent labelling on ultra-thin film chip. result shown that suitable Platform III streptavidin-biotin conjugation gives highest in both antibody immobilization antigen detection. limit 10 ng/ml also show there effect efficiency system orientation between antibody.
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ژورنال
عنوان ژورنال: Journal of physics
سال: 2022
ISSN: ['0022-3700', '1747-3721', '0368-3508', '1747-3713']
DOI: https://doi.org/10.1088/1742-6596/2346/1/012009