Sequence and structure evolved separately in a ribosomal ubiquitin variant

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Sequence and structure evolved separately in a ribosomal ubiquitin variant.

Encoded by a multigene family, ubiquitin is expressed in the form of three precursor proteins, two of which are fusions to the ribosomal subunits S27a and L40. Ubiquitin assists in ribosome biogenesis and also functions as a post-translational modifier after its release from S27a or L40. However, several species do not conserve the ribosomal ubiquitin domains. We report here the solution struct...

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ژورنال

عنوان ژورنال: The EMBO Journal

سال: 2007

ISSN: 0261-4189,1460-2075

DOI: 10.1038/sj.emboj.7601772