Sequence of ornithine decarboxylase from Lactobacillus sp. strain 30a
نویسندگان
چکیده
منابع مشابه
Genome Sequence of Lactobacillus saerimneri 30a (Formerly Lactobacillus sp. Strain 30a), a Reference Lactic Acid Bacterium Strain Producing Biogenic Amines
Lactobacillus sp. strain 30a (Lactobacillus saerimneri) produces the biogenic amines histamine, putrescine, and cadaverine by decarboxylating their amino acid precursors. We report its draft genome sequence (1,634,278 bases, 42.6% G+C content) and the principal findings from its annotation, which might shed light onto the enzymatic machineries that are involved in its production of biogenic ami...
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Lactic acid bacteria play a pivotal role in many food fermentations and sometimes represent a health threat due to the ability of some strains to produce biogenic amines that accumulate in foods and cause trouble following ingestion. These strains carry specific enzymatic systems catalyzing the uptake of amino acid precursors (e.g., ornithine and lysine), the decarboxylation inside the cell, an...
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Ornithine decarboxylase (OrnDCase; L-ornithine carboxy-lyase, EC 4.1.1.17) is the first and rate-limiting enzyme in the biosynthesis of polyamines in mammalian cells. During cell growth the enzyme is regulated by rapid changes in the level of its mRNA and protein. To explore the molecular basis of these changes, we cloned a full-length cDNA copy of the major 2.4-kilobase OrnDCase mRNA from mous...
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Histidine decarboxylase (HDC) from Lactobacillus 30a converts histidine to histamine, a process that enables the bacteria to maintain the optimum pH range for cell growth. HDC is regulated by pH; it is active at low pH and inactive at neutral to alkaline pH. The X-ray structure of HDC at pH 8 revealed that a helix was disordered, resulting in the disruption of the substrate-binding site. The HD...
متن کاملStrain polymorphism and tentative mapping of mouse ornithine decarboxylase.
SOURCE/DESCRIPTION The plasmld p0D45~contains a 1.6 kb of a omithine decarboxyiase cDNA . POLYMORPHISM Constant Eco RI bands vere found at 3.6, 4.4, 5.5, 6.9, 8.5, 11.5, 13.5 and 19 kb. Variant bands vere found at 4.7 and 6.2 kb. FREQUENCY The 4.7 band is present in BALB/c, not in C57BL/6, DBA/2 and C3Hf, and segregate in CxB recombinant inbred (RI) strains. The 6.2 kb band is present in DBA/2 ...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1994
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.176.23.7391-7394.1994