Sequential Delivery of Basic Fibroblast Growth Factor and Platelet-Derived Growth Factor for Angiogenesis
نویسندگان
چکیده
منابع مشابه
Metastasis in Human Melanoma Xenografts Fibroblast Growth Factor Promote Angiogenesis and Platelet-derived Endothelial Cell Growth Factor, and Basic Vascular Endothelial Growth Factor, Interleukin 8, Updated Version
Angiogenesis is a significant prognostic factor in melanoma, but the angiogenic factors controlling the neovascularization are not well defined. The purpose of this study was to investigate whether the angiogenesis and metastasis of melanoma are promoted by vascular endothelial growth factor (VEGF), interleukin 8 (IL-8), platelet-derived endothelial cell growth factor (PD-ECGF), and/or basic fi...
متن کاملVascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts.
Angiogenesis is a significant prognostic factor in melanoma, but the angiogenic factors controlling the neovascularization are not well defined. The purpose of this study was to investigate whether the angiogenesis and metastasis of melanoma are promoted by vascular endothelial growth factor (VEGF), interleukin 8 (IL-8), platelet-derived endothelial cell growth factor (PD-ECGF), and/or basic fi...
متن کاملVascular endothelial growth factor and basic fibroblast growth factor differentially modulate early postnatal coronary angiogenesis.
The roles of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF [FGF-2]) in early postnatal regulation of coronary angiogenesis were investigated by administering neutralizing antibodies to these growth factors between postnatal days 5 and 12. Immunohistochemistry and Western blotting both revealed decreases in VEGF protein in the hearts of rats treated with eith...
متن کاملPlatelet derived growth factor and fibroblast growth factor basic levels in the vitreous of patients with vitreoretinal disorders.
AIM To determine the potential role of basic fibroblast growth factor (bFGF) and platelet derived growth factor (PDGF) in the pathogenesis of proliferative vitreoretinopathy (PVR). METHODS An enzyme linked immunosorbent assay technique was used to determine the quantities of bFGF and PDGF in 38 vitreous samples taken from patients undergoing trans pars plana vitrectomy (PPV) for a variety of ...
متن کاملToward surgical angiogenesis using slow-released basic fibroblast growth factor.
OBJECTIVE Therapeutic angiogenesis using basic fibroblast growth factor (bFGF) in coronary artery disease has been documented in a number of papers. However, the effectiveness is discrepant among documents. In this study, we evaluated the distribution of bFGF in the rat heart by different administration methods, and investigated the efficacy of slow-released administration of bFGF using biodegr...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2011
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2010.0551