Shared paramyxoviral glycoprotein architecture is adapted for diverse attachment strategies

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Shared paramyxoviral glycoprotein architecture is adapted for diverse attachment strategies

Members within the paramyxovirus subfamily Paramyxovirinae constitute a large number of highly virulent human and animal pathogens. The glycoproteins present on these viruses are responsible for mediating host cell attachment and fusion and are key targets for the design of antiviral entry inhibitors. In the present review, we discuss recent structural studies which have led to a better underst...

متن کامل

Unusual molecular architecture of the machupo virus attachment glycoprotein.

New World arenaviruses, which cause severe hemorrhagic fever, rely upon their envelope glycoproteins for attachment and fusion into their host cell. Here we present the crystal structure of the Machupo virus GP1 attachment glycoprotein, which is responsible for high-affinity binding at the cell surface to the transferrin receptor. This first structure of an arenavirus glycoprotein shows that GP...

متن کامل

An Approach to Shared Infrastructure in Islamic-Iranian Architecture (Evidence-Based Design for Architecture Façades of the Qajar Period)

Given the changes that have taken place in recent centuries, many changes have occurred in the facade and its elements, and has caused turbulence in the visual appearance of buildings. However, throughout the history of the late Qajar and early period of the first Pahlavi era, architectural styles have been the continuation and complement of previous styles. In the history of Iranian architectu...

متن کامل

Attachment and Cognitive Architecture

Humans are interesting combinations of mammalian drives such as feeding, child rearing, and group affiliation, with high level cognitive capabilities such as language and planning. In this position paper, I argue that the attachment behavior system is an interesting boundary case to examine because, while attachment in young children is extremely similar attachment behavior in other primates, i...

متن کامل

Complement evasion of pathogens: common strategies are shared by diverse organisms.

Infectious diseases represent a major health problem. Based on the limited efficacy of existing drugs and vaccines and the increasing antibiotic resistance new strategies are needed to fight infectious diseases. A better understanding of pathogen-host interaction is one important aspect to identify new virulence factors and antimicrobial and anti-inflammatory compounds utilized by pathogens rep...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biochemical Society Transactions

سال: 2010

ISSN: 0300-5127,1470-8752

DOI: 10.1042/bst0381349