shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library
نویسندگان
چکیده
منابع مشابه
shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library
RNA interference (RNAi) screening is extensively used in the field of reverse genetics. RNAi libraries constructed using random oligonucleotides have made this technology affordable. However, the new methodology requires exploration of the RNAi target gene information after screening because the RNAi library includes non-natural sequences that are not found in genes. Here, we developed a web-ba...
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ژورنال
عنوان ژورنال: EURASIP Journal on Bioinformatics and Systems Biology
سال: 2016
ISSN: 1687-4153
DOI: 10.1186/s13637-016-0039-8