SIC, a Secreted Protein of Streptococcus pyogenesThat Inactivates Antibacterial Peptides
نویسندگان
چکیده
منابع مشابه
SIC, a secreted protein of Streptococcus pyogenes that inactivates antibacterial peptides.
Some isolates of the significant human pathogen Streptococcus pyogenes, including virulent strains of the M1 serotype, secrete protein SIC. This molecule, secreted in large quantities, interferes with complement function. As a result of natural selection, SIC shows a high degree of variation. Here we provide a plausible explanation for this variation and the fact that strains of the M1 serotype...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m301995200