Silicon µPCR Chip for Forensic STR Profiling with Hybeacon Probe Melting Curves
نویسندگان
چکیده
منابع مشابه
A forensic STR profiling system for the Eurasian badger: a framework for developing profiling systems for wildlife species.
Developing short tandem repeat (STR) profiling systems for forensic identification is complicated in animal species. Obtaining a representative number of individuals from populations, limited access to family groups and a lack of developed STR markers can make adhering to human forensic guidelines difficult. Furthermore, a lack of animal specific guidelines may explain why many wildlife forensi...
متن کاملDetermination of melting temperature and temperature melting range for DNA with multi-peak differential melting curves.
Many factors that change the temperature position and interval of the DNA helix-coil transition often also alter the shape of multi-peak differential melting curves (DMCs). For DNAs with a multi-peak DMC, there is no agreement on the most useful definition for the melting temperature, Tm, and temperature melting width, ΔT, of the entire DNA transition. Changes in Tm and ΔT can reflect unstable ...
متن کاملY Chromosome STR Analysis in Forensic Practice
Currently, the gradual introduction and routine application of validated Y chromosomal STR systems in stain analysis is being experienced. These systems are powerful forensic tools especially for the area of sexual assault evidence and are superior to autosomal systems for two reasons: the differential cell lysis step prior to the PCR is replaced by a sex chromosome selection during PCR and the...
متن کاملNext-Generation STR Genotyping Kits for Forensic Applications.
Forensic DNA typing has been a constantly evolving field driven by innovations from academic laboratories as well as kit manufacturers. Central to these technological advances has been the transition from multilocus-probe restriction fragment length polymorphism (RFLP) methods to short tandem repeat (STR) PCR-based assays. STRs are now the markers of choice for forensic DNA typing and a wide va...
متن کاملForensic Profiling System
Incidents related to hacking and network intrusion are on the increase. Most organizations safeguard themselves against cyber attacks by employing security methods such as encryption technologies, network monitoring tools, deploying firewalls and intrusion detection and response mechanisms. Even though prevention mechanisms are in place the vulnerabilities associated with any computer network o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-43946-5