Simple Limbal Epithelial Transplantation Method in The Treatment of Unilateral Limbal Stem Cell Deficiency Due to Chemical Burn

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Long-term Outcome of Limbal Stem Cell Transplantation for the Management of Total Limbal Stem Cell Deficiency due to a Chemical Burn

Purpose: To evaluate the long-term outcome of limbal stem cell transplantation (LSCT) for the management of total limbal stem cell deficiency (LSCD) due to chemical burn in Labbafinejad Medical Center (LMC). Methods: Records of patients with a history of severe (i.e. grade III and IV) chemical burns, who were referred to LMC and underwent LSCT, were reviewed and data including demographic chara...

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Management of Unilateral Limbal Stem Cell Deficiency by Simple Limbal Epithelial Transplantation – Our Experience

Simple Limbal Epithelial Transplantation (SLET) has been proposed recently for care of total Limbal Stem Cell Deficiency (LSCD) secondary to alkali burn of cornea [1]. Reportedly it combines advantages of conjunctival limbal auto grafting [2] and cultivated limbal epithelial transplantation [3] by being a single-stage, affordable procedure utilizing minimal donor tissue. Besides, it is also rep...

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Assessment of surgical outcomes of limbal transplantation using simple limbal epithelial transplantation technique in patients with total unilateral limbal deficiency.

This study aimed to evaluate the effectiveness of the novel simple limbal epithelial transplantation (SLET) technique, which reduces the risk of iatrogenic limbal stem cell deficiency in the donor eye. Four patients with total unilateral limbal stem cell deficiency received a limbal graft, measuring 4 mm × 2 mm, from the contralateral healthy eye in a single surgical procedure. The graft was di...

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Allo-limbal transplantation in patients with limbal stem cell deficiency.

AIM To report the outcome of a series of patients with stem cell deficiency who underwent allo-limbal transplantation and to describe a technique for this procedure. METHODS Six consecutive patients underwent allo-limbal stem cell transplantation. The primary diagnosis included alkali burn (n = 2), trachoma (n = 1), chronic rosacea blepharitis and kerato-conjunctivitis (n = 1), aniridia (n = ...

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Limbal Stem Cell Deficiency and Treatment with Stem Cell Transplantation

The cornea is the outermost tissue of the eye and it must be transparent for the maintenance of good visual function. The superficial epithelium of the cornea, which is renewed continuously by corneal stem cells, plays a critical role in the permanence of this transparency. These stem cells are localized at the cornea-conjunctival transition zone, referred to as the limbus. When this zone is af...

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ژورنال

عنوان ژورنال: European Eye Research

سال: 2021

ISSN: ['2757-8135']

DOI: https://doi.org/10.14744/eer.2021.32032