Simulation of ATP metabolism in cardiac excitation–contraction coupling

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Simulation of ATP metabolism in cardiac excitation-contraction coupling.

To obtain insights into the mechanisms underlying the membrane excitation and contraction of cardiac myocytes, we developed a computer model of excitation-contraction coupling (Kyoto model: Jpn. J. Physiol. 53 (2003) 105). This model was further expanded by incorporating pivotal reactions of ATP metabolism; the model of mitochondrial oxidative phosphorylation by Korzeniewski and Zoladz (Biophys...

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ژورنال

عنوان ژورنال: Progress in Biophysics and Molecular Biology

سال: 2004

ISSN: 0079-6107

DOI: 10.1016/j.pbiomolbio.2004.01.006