Single-cell patterning technology for biological applications
نویسندگان
چکیده
منابع مشابه
Surface Engineering and Patterning Using Parylene for Biological Applications
Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene “peel-off” stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensor...
متن کاملLaser-fabricated cell patterning stencil for single cell analysis
Precise spatial positioning and isolation of mammalian cells is a critical component of many single cell experimental methods and biological engineering applications. Although a variety of cell patterning methods have been demonstrated, many of these methods subject cells to high stress environments, discriminate against certain phenotypes, or are a challenge to implement. Here, we demonstrate ...
متن کاملSingle nanoparticle detectors for biological applications.
Nanoparticle research has become increasingly important in the context of bioscience and biotechnology. Practical use of nanoparticles in biology has significantly advanced our understanding about biological processes in the nanoscale as well as led to many novel diagnostic and therapeutic applications. Besides, synthetic and natural nanoparticles are of concern for their potential adverse effe...
متن کاملHigh-density, multiplexed patterning of cells at single-cell resolution for tissue engineering and other applications.
The ability to arrange distinct cells in specific, predefined patterns at single-cell resolution could have broad applications in tissue engineering, cell-based assays, cell and tissue cocultures, and fundamental studies of cell–cell interactions. In particular, the proper functioning of engineered constructs for tissue and organ transplantation requires positioning different cell types in anat...
متن کاملnDEP microwells for single-cell patterning in physiological media.
We present a novel technique to accurately position single cells on a substrate using negative dielectrophoresis and cell-substrate adhesion. The cells are suspended in physiological media throughout the patterning process. We also verify the biocompatibility of this method by demonstrating that the patterned cells proliferate and show normal morphology. We calculate the temperatures and transm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2019
ISSN: 1932-1058
DOI: 10.1063/1.5123518