Single-File Diffusion of Flagellin in Flagellar Filaments
نویسندگان
چکیده
منابع مشابه
Single-file diffusion of flagellin in flagellar filaments.
A bacterial flagellar filament is a cylindrical crystal of a protein known as flagellin. Flagellin subunits travel from the cytoplasm through a 2 nm axial pore and polymerize at the filament's distal end. They are supplied by a pump in the cell membrane powered by a proton-motive force. In a recent experiment, it was observed that growth proceeded at a rate of approximately one subunit every 2 ...
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The distribution of flagellin subunits in flagellar filaments synthesized by merodiploid strains carrying two distinguishable hag loci has been examined. The filament was found to be a homogeneous co-polymer of the two subunits. This suggests that the subunits may be able to mix freely before being assembled.
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Theoretical models of single-file transport in a homogeneous channel are considered. Three levels of channel populations were specified for which different approximations could be used. The results of these approximations are in good agreement with the results of a computer experiment (Aityan and Portnov 1986). At low populations, the pair correlation functions were negligibly small and allowed...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2013
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.05.030