Single Nucleotide Polymorphism (SNP)-Strings: An Alternative Method for Assessing Genetic Associations
نویسندگان
چکیده
منابع مشابه
Single Nucleotide Polymorphism (SNP)-Strings: An Alternative Method for Assessing Genetic Associations
BACKGROUND Genome-wide association studies (GWAS) identify disease-associations for single-nucleotide-polymorphisms (SNPs) from scattered genomic-locations. However, SNPs frequently reside on several different SNP-haplotypes, only some of which may be disease-associated. This circumstance lowers the observed odds-ratio for disease-association. METHODOLOGY/PRINCIPAL FINDINGS Here we develop a ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0090034