Single Prazosin Infusion in Prelimbic Cortex Fosters Extinction of Amphetamine-Induced Conditioned Place Preference
نویسندگان
چکیده
منابع مشابه
Single Prazosin Infusion in Prelimbic Cortex Fosters Extinction of Amphetamine-Induced Conditioned Place Preference
Exposure to drug-associated cues to induce extinction is a useful strategy to contrast cue-induced drug seeking. Norepinephrine (NE) transmission in medial prefrontal cortex has a role in the acquisition and extinction of conditioned place preference induced by amphetamine. We have reported recently that NE in prelimbic cortex delays extinction of amphetamine-induced conditioned place preferenc...
متن کاملAmphetamine Conditioned Place Preference in Planarians
Methand other amphetamines currently present major drug-abuse concerns. However, the demonstration and study of abuse-related behaviors expressed in animal models is expensive and time-consuming. We previously reported a novel model of conditioned place preference (CPP), which is a standard tool in abuse research, in invertebrates (planarians). In the present study, planarians were tested for l...
متن کاملBrief Communication Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference
Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference Ashley M. Blouin, Sungho Han, Anne M. Pearce, KaiLun Cheng, JongAh J. Lee, Alexander W. Johnson, Chuansong Wang, Matthew J. During, Peter C. Holland, Yavin Shaham, Jay M. Baraban, and Irving M. Reti Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryla...
متن کاملRole of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference.
Narp knockout (KO) mice demonstrate an impaired extinction of morphine conditioned place preference (CPP). Because the medial prefrontal cortex (mPFC) has been implicated in extinction learning, we tested whether Narp cells in this region play a role in the extinction of morphine CPP. We found that intracranial injections of adenoassociated virus (AAV) expressing wild-type (WT) Narp into the mP...
متن کاملEffects of adenosine receptor agonists and antagonists in amphetamine-induced conditioned place preference test in rats.
The influence of adenosine receptor agonists and antagonists on amphetamine-induced conditioned place preference (CPP) was examined in male Wistar rats. Selective adenosine A1 receptor agonist, CPA, significantly reduced the acquisition of CPP induced by amphetamine. NECA (A2/A1 adenosine receptor agonist) produced similar effect, but selective A2 adenosine receptor agonist CGS 21680, attenuate...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2017
ISSN: 1663-9812
DOI: 10.3389/fphar.2017.00530