Sirtuin 1 Modulation in Rat Model of Acetaminophen-Induced Hepatotoxicity
نویسندگان
چکیده
منابع مشابه
D-galactosamine/lipopolysaccharide-induced hepatotoxicity downregulates sirtuin 1 in rat liver: role of sirtuin 1 modulation in hepatoprotection.
D-Galactosamine/Lipopolysaccharide (D-GalN/LPS) is a well known model of hepatotoxicity that closely resembles acute liver failure (ALF) seen clinically. The role of sirtuin 1 in this model has not yet been documented. However, there have been a number of studies about the cytoprotective effects of resveratrol, a SIRT1 activator, in the liver. This study was aimed at elucidating the roles of SI...
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ژورنال
عنوان ژورنال: Physiological Research
سال: 2015
ISSN: 1802-9973,0862-8408
DOI: 10.33549/physiolres.933205