Skeletal muscle signaling response to concurrent endurance and resistance exercise

The Response of Skeletal Muscle-Expressed Neurotrophins to Acute Resistance Exercise in Male Wistar Rats

Background. BDNF and NT-4/5 have been proposed to be involved in the coordinated adaptations of the neuromuscular system to the elevated level of activity, but an activity-dependent expression of neurotrophins in skeletal muscle is not well established. Objectives. We, therefore, investigated the effect of one session of resistance exercise on mRNA expression of some neurotrophins in Slow and ...

The order of concurrent endurance and resistance exercise modifies mTOR signaling and protein synthesis in rat skeletal muscle.

Concurrent training, a combination of endurance (EE) and resistance exercise (RE) performed in succession, may compromise the muscle hypertrophic adaptations induced by RE alone. However, little is known about the molecular signaling interactions underlying the changes in skeletal muscle adaptation during concurrent training. Here, we used an animal model to investigate whether EE before or aft...

Resistance exercise induced mTORC1 signaling is not impaired by subsequent endurance exercise in human skeletal muscle.

The current dogma is that the muscle adaptation to resistance exercise is blunted when combined with endurance exercise. The suggested mechanism (based on rodent experiments) is that activation of adenosine monophosphate-activated protein kinase (AMPK) during endurance exercise impairs muscle growth through inhibition of the mechanistic target of rapamycin complex 1 (mTORC1). The purpose of thi...

Characteristics and Adaptation of Skeletal Muscle to Endurance Exercise

Skeletal Muscle Following Intense Endurance Exercise

Protein-leucine Ingestion Activates a Regenerative Inflammo-Myogenic Transcriptome in 1 Skeletal Muscle Following Intense Endurance Exercise 2 3 David S. Rowlands, Andre R. Nelson, Frederic Raymond, Sylviane Metairon, Robert 4 Mansourian, Jim Clarke, Trent Stellingwerff, Stuart M. Phillips 5 6 School of Sport and Exercise and Institute of Food Nutrition, and Human Health, Massey University, 7 W...