Skeletal muscle substrate metabolism during exercise: methodological considerations
نویسندگان
چکیده
منابع مشابه
Skeletal muscle energy metabolism during prolonged, fatiguing exercise.
A depletion of phosphocreatine (PCr), fall in the total adenine nucleotide pool (TAN = ATP + ADP + AMP), and increase in TAN degradation products inosine 5'-monophosphate (IMP) and hypoxanthine are observed at fatigue during prolonged exercise at 70% maximal O(2) uptake in untrained subjects [J. Baldwin, R. J. Snow, M. F. Carey, and M. A. Febbraio. Am. J. Physiol. 277 (Regulatory Integrative Co...
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An acute bout of exercise imposes a major challenge on whole-body metabolism and metabolic adjustments are needed in multiple tissues during recovery to reestablish metabolic homeostasis. It is currently unresolved how this regulation is orchestrated between tissues. This study was undertaken to clarify the role of skeletal muscle derived interleukin 6 (IL-6) in the coordination of the metaboli...
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Microneurographic measurements of muscle sympathetic nerve activity (SNA) have suggested that, during static exercise, central command is much less important than skeletal muscle afferents in causing sympathetic neural activation. The possibility remains, however, that the sympathetic discharge produced by central commandis targeted mainly to tissues other than skeletal muscle. To examine this ...
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In humans af ter short-term maximal exercise muscle glycogen levels are reduced to 75-80% of the initial muscle content. However, data obtained from maximally activated rat muscles show th at after only a few seconds of exercise total glycogen depletion had occurred in many fast fibres . It is argued that during short maximal exercise, effects of glycogen depletion in some fibres may lead to th...
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We compared in human skeletal muscle the effect of absolute vs. relative exercise intensity on AMP-activated protein kinase (AMPK) signaling and substrate metabolism under normoxic and hypoxic conditions. Eight untrained males cycled for 30 min under hypoxic conditions (11.5% O(2), 111 +/- 12 W, 72 +/- 3% hypoxia Vo(2 peak); 72% Hypoxia) or under normoxic conditions (20.9% O(2)) matched to the ...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1999
ISSN: 0029-6651,1475-2719
DOI: 10.1017/s0029665199001202