Sleep and inflammation in resilient aging

Sleep and inflammation in resilient aging

Sleep quality is important to health, and increasingly viewed as critical in promoting successful, resilient aging. In this review, the interplay between sleep and mental and physical health is considered with a focus on the role of inflammation as a biological pathway that translates the effects of sleep on risk of depression, pain and chronic disease risk in aging. Given that sleep regulates ...

Inflammation in Sleep Debt and Sleep Disorders

Not only sleep is an essential physiological function, but also plays important roles in promoting growth, maturation, and overall health. There is increasing interest regarding the impact of sleep and its disorders on the regulation of inflam-matory processes and end-organ morbidities, particularly in the context of neurocognitive, metabolic, and cardiovascular diseases and their complications...

Sleep and Human Aging

Older adults do not sleep as well as younger adults. Why? What alterations in sleep quantity and quality occur as we age, and are there functional consequences? What are the underlying neural mechanisms that explain age-related sleep disruption? This review tackles these questions. First, we describe canonical changes in human sleep quantity and quality in cognitively normal older adults. Secon...

Sleep and normal aging

Sleep and aging

This review describes normal and disordered sleep in the older adult population. Although several distinctive sleep changes across the lifespan are normative, including changes in the amount of time spent in different stages of sleep and a shift in the timing of circadian rhythms, sleep disorders are also common in late life. Sleep-disordered breathing, insomnia, circadian rhythm sleep-wake dis...