Small-angle scattering for structural biology-Expanding the frontier while avoiding the pitfalls
نویسندگان
چکیده
منابع مشابه
3D cell biology - the expanding frontier.
I am very pleased to introduce this Special Issue. When Michael Way invited me to serve as the inaugural Guest Editor at Journal of Cell Science, we discussed how to capture our mutual excitement about current research in 3D cell biology. My own research seeks to elucidate how molecularly regulated changes in cell behavior drive alterations in the structure and function of mammalian organs. Spe...
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ABSTRACT Background: Coherent scattering leads to diffraction effects and especially constructive interferences. Theseinterferences carry some information about the molecular structure of the tissue. As breast cancer isthe most widespread cancer in women, this project evaluated the application of small angleX-ray scattering (SAXS) for differentiation between normal and cancerous breast tissues....
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Intrinsically Disordered Proteins (IDPs) are fundamental actors of biological processes. Their inherent plasticity facilitates very specialized tasks in cell regulation and signalling, and their malfunction is linked to severe pathologies. Understanding the functional role of disorder requires the structural characterization of IDPs and the complexes they form. Small-angle Scattering of X-rays ...
متن کاملSmall angle neutron scattering
Small Angle Neutron Scattering (SANS) is a technique that enables to probe the 3-D structure of materials on a typical size range lying from ∼ 1 nm up to ∼ a few 100 nm, the obtained information being statistically averaged on a sample whose volume is ∼ 1 cm3. This very rich technique enables to make a full structural characterization of a given object of nanometric dimensions (radius of gyrati...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2010
ISSN: 0961-8368
DOI: 10.1002/pro.351