Small Molecule Probes of Cellular Pathways and Networks
نویسندگان
چکیده
منابع مشابه
Small molecule probes that target Abl kinase.
Two different strategies, namely a dialdehyde-based cross-linking and photo-affinity labeling, have been developed to generate small molecule activity-based probes (ABPs) for the Abelson (Abl) tyrosine kinase, of which probe 13, derived from the photo-affinity approach, showed specific labeling of Abl kinase present in a crude mammalian proteome.
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2010
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb1002976