SNPdbe: constructing an nsSNP functional impacts database

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SNPdbe: constructing an nsSNP functional impacts database

UNLABELLED Many existing databases annotate experimentally characterized single nucleotide polymorphisms (SNPs). Each non-synonymous SNP (nsSNP) changes one amino acid in the gene product (single amino acid substitution;SAAS). This change can either affect protein function or be neutral in that respect. Most polymorphisms lack experimental annotation of their functional impact. Here, we introdu...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2011

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btr705