SOLUBILITY CURVES OF MIXTURES AND SOLID SOLUTIONS

Prediction of Satranidazole Solubility in Water-Polyethylene Glycol 400 Mixtures Using Extended Hildebrand Solubility Approach

       The Extended Hildebrand Solubility Parameter Approach (EHSA) is used to estimate the solubility of satranidazole in binary solvent systems. The solubility of satranidazole in various water-PEG 400 mixtures was analyzed in terms of solute-solvent interactions using a modified version of Hildebrand-Scatchard treatment for regular solutions. The solubility equation employs term interaction ...

Enhanced Solubility and Bioavailability of Apigenin via Preparation of Solid Dispersions of Mesoporous Silica Nanoparticles

In this study, a novel mesoporous silica nanoparticles drug carrier contributes to improving the solubility, dissolution, and the oral bioavailability of apigenin (AP). The apigenin of solid dispersion of mesoporous silica nanoparticles (AP-MSN) was prepared by physical absorption method and also, in-vitro drug release and in-vivo bioavailability performance were evaluated. Based on its solubil...

Enhanced Solubility and Bioavailability of Apigenin via Preparation of Solid Dispersions of Mesoporous Silica Nanoparticles

In this study, a novel mesoporous silica nanoparticles drug carrier contributes to improving the solubility, dissolution, and the oral bioavailability of apigenin (AP). The apigenin of solid dispersion of mesoporous silica nanoparticles (AP-MSN) was prepared by physical absorption method and also, in-vitro drug release and in-vivo bioavailability performance were evaluated. Based on its solubil...

performance of solubility models for prediction of acetaminophen solubility in binary and ternary solvent mixtures of ethanol, water and glycerin

Solubility, Viscosity and Density of Refrigerant/Lubricant Mixtures

Solubility (vapor pressure) , viscosity and density have been experimentally determined for thirty-five potential refrigeration working fluids. Properties for low refrigerant concentration mixtures (0, 10, 20 and 30 weight percent refrigerant) were determined over the temperature range 0 to IOO•C (32 to 212"F) or to the critical temperature of the refrigerant, and pressure range 0 to 3,500 kPa ...