Sophorolipids Having Enhanced Antibacterial Activity

Enhanced Antibacterial Activity of MGO

Background: Manuka honey is recognized for it’s health-promoting properties and it’s use in medicine is well documented. However, the actions of Manuka honey are limited by rapid digestion and the inactivation of bioactive components such as methylglyoxal. Cyclodextrins are naturally occurring glucose rings that improve stability and bioactivity of products. This study investigates the tolerabi...

Vorinostat Pretreatment Enhanced Ciprofloxacin-Induced Antibacterial Activity

The mechanism of ciprofloxacin action involves interference with transcription and replication of bacterial DNA, which results in elevated oxidative stress, and bacterial cell death. Vorinostat was shown to induce oxidative DNA damage. In the current work, the possibility for interactive effect of vorinotat on ciprofloxacin-induced cytotoxicity against a number of reference bacteria was investi...

Sophorolipids Having Enhanced Anti-bacterial Activity Sophorolipids (SLs) are glycolipids produced fermentatively by yeast such as Candida bombicola, Candida apicola and Wickerhamiella domercqiae and composed of a dimeric sugar linked with a glycosidic bond to a hydroxyl fatty acid. SLs

Sophorolipids (SLs) are glycolipids produced fermentatively by yeast such as Candida bombicola, Candida apicola and Wickerhamiella domercqiae and composed of a dimeric sugar linked with a glycosidic bond to a hydroxyl fatty acid. SLs have gained interest in pharmaceutical arena because of its wide array of therapeutic benefits. Shah et al. 1 first reported that natural SLs and its first generat...

solid lipid nanoparticles of ciprofloxacin hydrochloride with enhanced antibacterial activity

Enhanced antibacterial activity in Hydra polyps lacking nerve cells.

The nervous system evolved within cnidarians. When assessing antibacterial activity in the freshwater polyp Hydra, we observed a strong correlation between the number of neurons present and the antibacterial activity. Tissue lacking neurons had a drastically enhanced antibacterial activity against Gram-positive (Bacillus subtilis) and Gram-negative (E. coli) bacteria compared to control tissue....