Spatial Dynamic Functional Connectivity Analysis Identifies Distinctive Biomarkers in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Disordered functional connectivity in schizophrenia.
The first functional neuroimaging studies of schizophrenia, using single photon (SPET) and positron emission tomography (PET), led to the notion of abnormal 'hypofrontality' (Ingvar & Franzen, 1974). Although consistent with data linking schizophrenia with deficits in frontal function, the popularity of'hypofrontality' gradually faded as technically and methodologically more sophisticated studi...
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Schizophrenia is a psychotic disorder characterized by functional dysconnectivity or abnormal integration between distant brain regions. Recent functional imaging studies have implicated large-scale thalamo-cortical connectivity as being disrupted in patients. However, observed connectivity differences in schizophrenia have been inconsistent between studies, with reports of hyperconnectivity an...
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We explored fronto-temporal connectivity using fMRI of patients and controls generating inner speech. Method The subjects were eight schizophrenic patients in remission recruited from the wards and clinics of the Maudsley Hospital, and 8 controls matched for age, sex and IQ. Diagnosis was made by clinical interview and case-note review, using DSM IV criteria. All subjects were trained to overtl...
متن کاملAltered functional and anatomical connectivity in schizophrenia.
BACKGROUND Schizophrenia is characterized by a lack of integration between thought, emotion, and behavior. A disruption in the connectivity between brain processes may underlie this schism. Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) were used to evaluate functional and anatomical brain connectivity in schizophrenia. METHODS In all, 29 chronic schizophrenia...
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BACKGROUND Schizophrenia is characterized by altered resting-state functional connectivity. Most previous studies have focused on changes in connectivity strengths; however, the alterations in connectivity density in schizophrenia remain largely unknown. Here, we aimed to investigate changes in resting-state functional connectivity density (rsFCD) in schizophrenia. METHODS A total of 95 schiz...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2019
ISSN: 1662-453X
DOI: 10.3389/fnins.2019.01006