Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues
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چکیده
منابع مشابه
Engineering osteochondral constructs through spatial regulation of endochondral ossification.
Chondrogenically primed bone marrow-derived mesenchymal stem cells (MSCs) have been shown to become hypertrophic and undergo endochondral ossification when implanted in vivo. Modulating this endochondral phenotype may be an attractive approach to engineering the osseous phase of an osteochondral implant. The objective of this study was to engineer an osteochondral tissue by promoting endochondr...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2018
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2018.04.025