منابع مشابه
Sphingomyelin lipidosis in a cat.
A 7-month-old Balinese cat with progressive neurological dysfunction had histopathological lesions of brain, liver, kidney, spleen, and lung consistent with a lysosomal storage disease. Ultrastructural examination revealed lysosomal hypertrophy with membranous inclusions. Hepatic sphingomyelin and cholesterol were elevated 10 times normal, and total phospholipids were increased 3.6 fold. Sphing...
متن کاملPathways of sphingomyelin metabolism in cultured fibroblasts from normal and sphingomyelin lipidosis subjects.
The metabolism of endogenous sphingomyelin labeled with 32P or [methyl-3H]choline and of exogenous [choline-methyl-3H], [32P]-, or [N-acyl-1-14C]sphingomyelin was studied in normal and Niemann-Pick Type A (NP-A) cultured fibroblasts. Despite a greater than 96% decrease in lysosomal sphingomyelinase activity in the NP-A cells, they were able to degrade endogenously produced [32P]- or [methyl-3H]...
متن کاملRefeeding syndrome in a cat with hepatic lipidosis.
Refeeding syndrome is characterized by severe hypophosphatemia occurring in patients given enteral or parenteral nutrition after severe weight loss. There are few veterinary reports that describe this syndrome but it is well documented in human medicine. This report describes a case of a domestic shorthair cat diagnosed with hepatic lipidosis following a 4-week history of decreased appetite and...
متن کاملSphingomyelin of red blood cells in lipidosis and in dementia of unknown origin in children.
Histological and chemical examinations of biopsy specimens from cerebral tissue of children suffering from undiagnosed progressive brain disease are performed increasingly. Important information is provided, which, though rarely of therapeutic value, does increase precision of diagnosis, prognosis, and genetic advice (Cumings, 1965a, b, c; Poser, 1962; Adams, 1965). This is especially true of t...
متن کاملLipid abnormalities in foam cell reticulosis of mice, an analogue of human sphingomyelin lipidosis.
The lipid changes in the inheritable foam cell reticulosis of mice discovered by Lyons, Hulse, and Rowe have been reexamined. The major abnormality in thymuses from homozygous-abnormal animals has been identified as an increase in the concentration (per milligram of protein) of sphingomyelin and cholesterol. This increase is associated with normal sphingomyelin-cleaving activity. The lipid comp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 1987
ISSN: 0300-9858,1544-2217
DOI: 10.1177/030098588702400504