Spines, Plasticity, and Cognition in Alzheimer's Model Mice
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چکیده
منابع مشابه
Spines, Plasticity, and Cognition in Alzheimer's Model Mice
The pathological hallmarks of Alzheimer's disease (AD)--widespread synaptic and neuronal loss and the pathological accumulation of amyloid-beta peptide (Aβ) in senile plaques, as well as hyperphosphorylated tau in neurofibrillary tangles--have been known for many decades, but the links between AD pathology and dementia and effective therapeutic strategies remain elusive. Transgenic mice have be...
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ژورنال
عنوان ژورنال: Neural Plasticity
سال: 2012
ISSN: 2090-5904,1687-5443
DOI: 10.1155/2012/319836